
FOBISIN 101
CAS No. 1370281-06-3
FOBISIN 101( FOBISIN101 )
Catalog No. M11527 CAS No. 1370281-06-3
FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 873 | In Stock |
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50MG | 1782 | In Stock |
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100MG | 2250 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameFOBISIN 101
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NoteResearch use only, not for human use.
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Brief DescriptionFOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.
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DescriptionFOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively; effectively blocks the ability of all seven 14-3-3 isoforms to stimulate exoenzyme S (ExoS) ADP-ribosyltransferase (IC50=6-19 uM in a functional assay); also blocked the binding of 14-3-3 with Raf-1 and proline-rich AKT substrate, PRAS40.
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In Vitro——
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In Vivo——
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SynonymsFOBISIN101
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PathwayOthers
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Target14-3-3 Protein
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Recptor14-3-3 Protein
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Research Area——
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Indication——
Chemical Information
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CAS Number1370281-06-3
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Formula Weight461.209
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Molecular FormulaC15H11N3Na3O8P
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name4-[(2Z)-2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydrazinyl]benzoate trisodium salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Zhao J, et al. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16212-6.
2. Du Y, et al. J Biomol Screen. 2006 Apr;11(3):269-76.
3. Fu H, et al. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2320-4.
molnova catalog



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