Cart
sales@molnova.com
Home - Products - Others - 14-3-3 Protein - FOBISIN 101

FOBISIN 101

CAS No. 1370281-06-3

FOBISIN 101( FOBISIN101 )

Catalog No. M11527 CAS No. 1370281-06-3

FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 In Stock
50MG 1782 In Stock
100MG 2250 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    FOBISIN 101
  • Note
    Research use only, not for human use.
  • Brief Description
    FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively.
  • Description
    FOBISIN 101 is a small molecule 14-3-3 protein-protein interaction inhibitor with IC50 of 9.3 and 16.4 uM for the binding of 14-3-3ζ or 14-3-3γ to PRAS40, respectively; effectively blocks the ability of all seven 14-3-3 isoforms to stimulate exoenzyme S (ExoS) ADP-ribosyltransferase (IC50=6-19 uM in a functional assay); also blocked the binding of 14-3-3 with Raf-1 and proline-rich AKT substrate, PRAS40.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FOBISIN101
  • Pathway
    Others
  • Target
    14-3-3 Protein
  • Recptor
    14-3-3 Protein
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1370281-06-3
  • Formula Weight
    461.209
  • Molecular Formula
    C15H11N3Na3O8P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    4-[(2Z)-2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydrazinyl]benzoate trisodium salt

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhao J, et al. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16212-6. 2. Du Y, et al. J Biomol Screen. 2006 Apr;11(3):269-76. 3. Fu H, et al. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2320-4.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Difopein

    A specific, competitive inhibitor of 14-3-3/ligand interactions with high affinity.

  • RB-011

    A small molecule that disrupt 14-3-3 dimers at low micromolar concentrations and induce rapid down-regulation of Raf-MAPK and PI3K-Akt signaling in Jurkat cells.

  • Fusicoccin-A

    A small-molecule stabilizer of 14-3-3 protein-protein interactions that stabilizes the complex between 14-3-3 and the stress response regulator GCN1.

Sign In Join Free